- เข้าร่วม
- 4 ก.ย. 2023
- ข้อความ
- 1
- กระทู้ ผู้เขียน
- #1
This was obtained from a meta-analysis of three studies (332 participants), one of which compared pregabalin with an antidepressant class drug (amitriptyline), one with a type of anti-inflammatory (celecoxib), and a paracetamol combined with an opioid ( Tramacet). . There was no benefit when pregabalin was given together with the opioids tapentadol (SMD -0.04, 95% CI -0.26 to +0.18; 1 study, 306 participants) or buprenorphrine Sciatiease Reviews . , 44 participants). There was a small benefit when pregabalin was combined with celecoxib compared with celecoxib Sciatiease alone (SMD -0.81, 95% -1.29 to -0.33; one study, 72 participants). Adverse events were more common with gabapentin and included dizziness (relative risk (RR) 1.99, 95% CI 1.17 to 3.37), fatigue (RR 1.85, 95% CI 1.12 to 3.05), difficulty thinking (RR 3.34, 95% CI 1. 54 to 3.37). 7.25) and visual disturbances (RR 5.72, 95% CI: 1.94 to 16.91).
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